Vaccine could halt autoimmune diseases such as rheumatoid arthritis and Chrohn’s

  • Potential treatment proved successful in animal studies
  • Could help tackle range of conditions including cancer

By
Sadie Whitelocks

Last updated at 11:55 AM on 26th December 2011

A simple vaccine could prevent the onset for autoimmune diseases such as rheumatoid arthritis and Chrohn's

A simple vaccine could prevent the onset for autoimmune diseases such as rheumatoid arthritis and Chrohn’s

A simple vaccine could stop the onset of autoimmune diseases such as rheumatoid arthritis and Chrohn’s, say scientists.

The potential treatment has proved successful in animal studies and it is hoped the breakthrough could lead to new ways of tackling a range of conditions including cancer.

Autoimmune diseases occur when the immune system mistakes some parts of the body as a pathogen and starts attacking its own cells.

But the new vaccine, based on nanotechnology, stops this process without causing severe side effects.

Lead researcher Professor Irit Sagi, from the Weizmann
Institute in Rehovot, Israel, hailed the discovery and believes it could prompt more effective treatments.

He said: ‘We are excited not only by the
potential of this method to treat Crohn’s, but by the potential of using
this approach to explore novel treatments for many other diseases.’

Professor Sagi and his team treated mice with a rodent version of Crohn’s, which is a chronic condition that causes inflammation in the gut.

Results showed that untreated mice suffered severe damage
to their colons while those injected with the vaccine experienced only ‘limited’ symptoms.

Authors highlight in the journal Nature Medicine. that the new approach is
extremely precise, and more effective than previous attempts.

Yeda, the technology transfer arm of the
Weizmann Institute, has already applied for patents on the vaccine.

However further testing is now needed before experts can be sure the therapy is safe for humans.

Rheumatoid arthritis is estimated to affect 400,000 people in England and Wales while there are currently 90,000 people living with Crohn’s disease in the UK.

Currently there is no cure for either autoimmune disease and the exact trigger of the condition remains unknown.

Here’s what other readers have said. Why not add your thoughts,
or debate this issue live on our message boards.

The comments below have not been moderated.

A pity both the headline and the article misspell the disease as Chrohn’s. An even greater pity it took people in the know (I didn’t but soon found out) to tell the DM – which then ignored them. It was good the DM published the article. Not so good is its standard of journalism.

How about looking at the evidence that vaccines could cause auto-immune disease in the first place.
– karen, tonbridge, 26/12/2011 16:59
***********they’re not going to do that are they – wouldn’t be profitable.

I have ankylosing spondylitis, which is similar to crohn’s disease, I hope it could cure that. Anyone that has it will know it is agony, but I now take HUMIRA once every 2 weeks, which is like a god send! Although there are many possible side effects so far been taking it over a year, and no trouble, and prevents any painfull joint pain so I can lead a normal life! so before people are quick to critise these the researchers because of side effects I praise them for creating a drug that was life changing for me!

I really hope this is true – my partner has psoriasis which is also a chroinc autoimmune disease and treated with exactly the same drugs as crohns and RA.

Sissy, thank you thank you, that I am not the only one who is noticing the awful spelling mistakes in the DM.
As I have said before, what has happened to standards.

Sissy, thank you thank you, that I am not the only one who is noticing the awful spelling mistakes in the DM.
As I have said before, what has happened to standards.

I really hope this comes to some good. As a sufferer of sarcoidosis I understand the importance of this work. Keep it up and good luck!

How about looking at the evidence that vaccines could cause auto-immune disease in the first place.

Oh I do hope this is true, I
Have rheumatoid arthritis I
have to take drugs and inject myself once a week with methotrexate which makes me do sick and once a fortnight with Cimzia. A vaccine would be winderful if it worked.

Vaccine based on nanotechnology! well the current crop of medicines-biologicals- are effective but sometimes have terrible side effects, often for life, moreover, recently there have been deaths. These biologicals are made from mice antibodies. I wouldn’t take a vaccine that has not been investigated properly, considering the recent flu vaccines that have also caused untold illnesses. Medicine should cure you, not make you worse or kill you. Get money out of medicine

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