Study Ties Infant Birth Weight to Mothers’ Breast Cancer Risk

TUESDAY, July 17 (HealthDay News) — Women who give birth to
large infants may have a more than twofold increased risk of developing
breast cancer, according to a new study.

Having a large baby may be associated with higher concentrations of
certain pregnancy hormones that boost the chances of breast cancer
development and progression, the researchers at the University of Texas
Medical Branch at Galveston suggested.

The team analyzed data from two long-term U.S. studies and found that
women who gave birth to the largest babies were 2.5 times more likely to
develop breast cancer than those who gave birth to the smallest
babies.

The increased risk associated with a baby’s weight was independent of
the mother’s birth weight and traditional breast cancer risk factors, the
investigators found.

In addition, the study authors noted, women who gave birth to the
largest babies were 25 percent more likely to have higher concentrations
of hormones that affect infant birth weight and breast cancer risk.

The news from the study, which is published in the July 17 issue of the
journal PLoS One, may help improve prediction and prevention of
breast cancer decades before it appears, the researchers said.

“Women can’t alter their pregnancy hormones, but can take steps to
increase their general protection against breast cancer,” study lead
author Dr. Radek Bukowski, a professor of obstetrics and gynecology, said
in a university news release.

Breast-feeding, having more than one child, healthy eating and
exercising have been shown to reduce breast cancer risk, Bukowski
noted.

The researchers pointed out that while the study found an association
between hormonal levels and infant birth weight and maternal breast cancer
risk, it did not prove a cause-and-effect relationship. They added that
more study is needed.

More information

The U.S. National Cancer Institute has more about breast cancer prevention.

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