Study Links Colic in Infants to Migraines in Moms

MONDAY, Feb. 20 (HealthDay News) — Experts are beginning to
believe some that some non-headache health problems in childhood — such
as vomiting and vertigo — might be linked to migraines later in life.
Now, a new study suggests a connection between mothers with migraines and
colic in infancy.

Colic is a condition marked by excessive crying in an otherwise healthy
child.

“Mothers with a history of migraine were more than two-and-a-half times
more likely to have a baby with colic than mothers who didn’t have
migraine,” said study author Dr. Amy Gelfand, a pediatric neurologist with
the Headache Center at the University of California, San Francisco.

The findings were released online Feb. 20 and Gelfand and colleagues
will present them in April at the American Academy of Neurology’s annual
meeting in New Orleans.

The researchers developed a questionnaire to help pinpoint whether a
baby had colic and to identify mothers who had been diagnosed with a
migraine, a condition believed to have a strong genetic link.

“We surveyed the mothers when they brought their babies into the
pediatrician’s office for their two-month well-baby check-up,” Gelfand
said.

Data from 154 mothers and their babies showed that nearly 29 percent of
the babies whose mothers had a history of migraine had colic, compared
with about 11 percent of babies whose moms did not report migraines.

“There was a trend when fathers answered the survey, too,” Gelfand
added. She said 93 survey-takers answered paternal migraine history
questions. The results: about 22 percent of colicky babies had a father
with migraine compared to only nearly 10 percent of the babies who did not
have the condition.

Chronic and often disabling, migraine headaches affect more than 29
million Americans, according to the U.S. Department of Health and Human
Services’ Office on Women’s Health.

Three-quarters of migraine sufferers are women and previous research
suggests about half of migraine sufferers remain undiagnosed.

“The bottom line is that migraine is an inherited disorder that
involves the whole body,” said neurologist and pain medicine specialist
Dr. Joel Saper, director of the Michigan Headache Neurological
Institute, in Ann Arbor.

Saper, who was not involved in the study, said people who are prone to
migraine react to overstimulation throughout the course of their lives. He
said the new research suggests “it’s very possible colic is an early
manifestation of migraine.”

Saper explained that babies and children have immature nervous systems
that don’t work the same way as an adult’s. He said migraine — a
neurological condition — might manifest differently in babies and
children.

“The underlying pathophysiology might be the same, but the reflexes are
different,” Saper said.

The researchers said colic did not appear to be linked to the sex of a
child. Also, while they did not ask whether babies were breast- or
bottle-fed, other studies suggest colic rates do not differ for the two
groups of infants, Gelfand noted. She said it’s still being debated
whether cow’s milk protein might play a role in some children, though.

Currently, most parents are advised to wait out the weeks or months it
takes for colic to resolve, to sooth and hold their baby, and to ask for
help — a parent time-out — if the chronic crying frays nerves.

Commenting on the study, pediatrician Dr. Tai Lockspeiser, an assistant
professor of pediatrics at the University of Colorado School of Medicine
and Children’s Hospital Colorado, said, “All babies cry and colic is just
one end of the spectrum.” She recommends “the 5 S’s System” made popular
by Dr. Harvey Karp: swaddling, sucking, side-lying, shushing and swaying.
“There are some great YouTube videos of this online that demonstrate
exactly what these are,” Lockspeiser said.

For her part, Gelfand said that “it’s too early to change any kind of
protocol for colic. But this gives pediatricians and neurologists another
hypothesis to consider. Parents could try non-medication strategies that
help some adult migraine sufferers, she said.

“Turning down loud music, going to a quiet room and decreasing
stimulation might help,” Gelfand said. She also suggested moms and dads
keep a “crying diary” to track when colic flare-ups tend to occur and
anything that seems to calm the baby.

Saper said the new research offers another clue into the evolution of
migraine in an individual. “We are now able to say this child may be on a
pathway.”

The next research step will be to follow the babies over the years,
said Gelfand.

“Right now we’re using the mothers’ migraines, but what we really want
to know is do these babies themselves go on to have migraine,” she
said.

The data and conclusions of this research should be viewed as
preliminary until published in a peer-reviewed journal.

More information

Visit Nemours to learn about colic.

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