Study Finds Link Between Heart Failure, Brain Changes

WEDNESDAY, Feb. 1 (HealthDay News) — Heart failure is associated with
a loss of gray matter in the brain and a decline in mental processes,
according to a new study.

These changes can make it more difficult for heart failure patients to
remember and perform health care instructions such as taking the correct
medications at the right times, the Australian researchers said.

They conducted memory and other mental performance tests on 35 heart
failure patients, 56 patients with ischemic heart disease (which sometimes
but not always accompanies heart failure), and 64 healthy people. MRI
exams were used to assess gray matter volume in different parts of the
brain.

In heart failure, the heart muscle is unable to pump enough oxygen-rich
blood to the body, while ischemic heart disease affects the supply of
blood to the heart.

Heart failure patients had worse immediate and long-term memory and
reaction speeds than healthy people. The brain scans showed that heart
failure was associated with losses of gray matter in areas believed to be
important for memory, reasoning and planning.

The study appears online Feb. 1 in the European Heart
Journal
.

“What we found in this study is that both ischemic heart disease and
heart failure are associated with a loss of cells in certain brain regions
that are important for the modulation of emotions and mental activity —
such a loss is more pronounced in people with heart failure, but can also
be seen in people with ischemic heart disease without heart failure,”
Osvaldo Almeida, director of research at the Western Australia Centre for
Health and Ageing in Perth, said in a journal news release.

People with both kinds of heart conditions “show subtle deficits in
cognitive abilities” compared to healthy people, Almeida said. However,
the researchers could not determine whether people with heart failure
performed worse than those with ischemic heart disease.

Almeida said the findings “are consistent with the possibility that
patients with heart failure may have trouble following complex management
strategies, and, therefore, treatment messages should be simple and clear.
Health professionals and patients need to be aware that problems caused by
heart disease are not limited to the heart.”

More information

The U.S. National Heart, Lung, and Blood Institute has more about heart failure.

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