Smoking May Up Cancer Risk in Barrett’s Esophagus Patients

FRIDAY, Feb. 10 (HealthDay News) — People with the condition
called Barrett’s esophagus who are smokers may have double the risk of
developing esophageal cancer, a new study warns.

These people also have twice the risk of developing advanced
precancerous cells, according to the study in the February issue of
Gastroenterology.

“We found that tobacco smoking emerged as the strongest lifestyle risk
factor for cancer progression. Contrary to popular belief, alcohol
consumption didn’t increase cancer risk in this group of patients with
Barrett’s esophagus,” lead author Helen Coleman, of Queen’s University
Belfast in Northern Ireland, said in a news release from the American
Gastroenterological Association.

In people with Barrett’s esophagus, damage caused by stomach acid
causes the lining of the esophagus to become similar to the lining of the
stomach, according to the U.S. MedlinePlus Medical Encyclopedia. Most
people with Barrett’s esophagus do not develop esophageal cancer.

For the study, researchers looked at more than 3,000 Barrett’s
esophagus patients worldwide and identified 117 cases of dysplasia or
cancers of the esophagus or stomach.

Current smoking, regardless of the number of cigarettes smoked per day,
was significantly associated with an increased risk of esophageal cancer.
Therefore, cutting down on cigarette consumption may not be enough to
reduce the risk of esophageal cancer in people with Barrett’s esophagus,
the researchers suggested.

“Tobacco smoking has been long established as highly carcinogenic,”
Coleman said. “Barrett’s esophagus patients who smoke should start a
cessation program immediately.”

Although the study authors pointed out that more research is needed to
confirm the findings, and the association noted in the study did not prove
a cause-and-effect relationship between smoking and esophageal cancer in
these patients, Coleman’s team suggested that smoking should be
discouraged.

The investigators also noted that developed countries have seen a rise
in the incidence of esophageal cancer.

More information

The U.S. National Cancer Institute has more about esophageal cancer prevention.

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