Scientists Probe the Origins of Dyslexia

WEDNESDAY, Dec. 21 (HealthDay News) — Problems in how people
with dyslexia process the sounds they hear may be at the heart of this
learning disorder, new research suggests.

The study findings, published in the Dec. 22 issue of the journal
Neuron, may one day lead to better therapies for children and
adults who are diagnosed with this common yet still ultimately mysterious
condition.

And different people with dyslexia may have differences in
brain-processing patterns, which could help distinguish subtypes of the
disorder.

Dyslexia affects about 5 percent of school-aged children.

Although we “typically think of dyslexia as an impairment of reading or
the printed word, previous research has suggested that there’s an
auditory-processing component. . . It’s not just the printed word but also
auditory,” said Dr. Andrew Adesman, who was not involved with the study
but is familiar with the findings.

Indeed, one of the biggest risk factors for dyslexia is delays in
spoken language in young children, said Adesman, chief of developmental
and behavioral pediatrics at the Steven Alexandra Cohen Children’s
Medical Center of New York, in New Hyde Park.

Previous brain imaging studies had shown abnormal processing of brief
sounds in people with dyslexia, but it has been unclear what the
neurophysiological mechanism was behind the abnormalities, according to
study authors Katia Lehongre, from the Ecole Normale Superieure in Paris,
and colleagues.

The French authors focused on a phenomenon called “sampling,” which
refers to how the brain initially responds to sounds. Specifically,
sampling involves the processing of phonemes, which are the basic elements
of sound.

“They’re looking at where and how sound is processed,” Adesman
explained.

What the investigators found in people with dyslexia, as compared to
people who did not have dyslexia (control-group members), were
abnormalities in the left auditory cortex of the brain.

The brains of people with dyslexia may “overreact” to phonemes at
high-frequency rhythms. This could interfere with verbal memory and,
hence, speech, the study found.

“The left auditory cortex may be less responsive to certain sound
frequencies that are optimal [for processing] phonemes,” Adesman
explained.

Although the research is “important,” said Dr. Harold Levinson,
clinical/research director of the Levinson Medical Center for Learning
Disabilities in Great Neck, N.Y., it may not take into account the
complexity of dyslexia and the many brain processes involved.

The particular brain abnormalities identified in this study may just
be a reflection of other problems in the cerebellum region of the brain,
he said.

A number of questions remained unanswered, Levinson added.

More information

The U.S. National Library of Medicine has more on dyslexia.

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