Runners May Live Longer

MONDAY, June 4 (HealthDay News) — Runners appear to live longer,
new research suggests.

But there is likely a tipping point, concluded the authors of another
new study that looked at the cardiovascular health of endurance athletes,
when the heart no longer benefits and may even suffer damage.

The first study, by researchers from the University of South Carolina
and the Ochsner Health System, in New Orleans, was presented Saturday at
the American College of Sports Medicine meeting, in San Francisco. It
analyzed the link between running and cardiovascular-related deaths in
nearly 53,000 adults. Research presented at medical meetings should be
viewed as preliminary until published in a peer-reviewed medical
journal.

The participants were between the ages of 20 and 100 and had undergone
a medical exam between 1971 and 2003. All were free of heart disease,
cancer and diabetes at the start of the study.

The researchers gleaned information from questionnaires in which the
participants reported their leisure-time activities, including their
running habits; about 27 percent said they ran.

The scientists used data from the National Death Index and found that
the runners had about a 20 percent lower mortality rate than the
non-runners, said lead researcher Dr. Chip Lavie, medical director of
cardiac rehabilitation and prevention at John Ochsner Heart and Vascular
Institute, in New Orleans.

Running lowered the risk for mortality when a person did not exceed
more than 20 miles a week, log more than five to seven miles per hour, or
run more than two to five times a week, the authors reported.

“Although higher doses [of running] are not associated with worse
outcomes when compared with non-runners, those with higher doses of
distance, frequency and speed seemed to lose the survival advantage gained
at lower doses of running,” Lavie noted.

Another study, published in the June issue of the Mayo Clinic
Proceedings
, reviewed the scientific literature on the effect of
extreme endurance training — such as that performed by marathoners,
triathletes, professional cyclists and ultra-marathon runners — and found
it can lead to long-term heart damage.

“There’s probably nothing better a person can do for themselves for
their long-term health than daily exercise,” said Dr. James O’Keefe, lead
author of the second study and a professor of medicine at the University
of Missouri and Saint Luke’s Hospital in Kansas City, Mo. “But if you
train more than the cardiovascular system is designed to handle, you can
tax your heart and do damage.”

He pointed out that the certain cardiovascular biomarkers become
elevated during extreme training in some athletes.

“Even though they go back to normal within a week, over months and
years, the elevations may lead to heart damage and increased
susceptibility to certain types of arrhythmias,” O’Keefe said.

He also noted that in one recent study, 12 percent of apparently
healthy marathon runners showed “patchy myocardial scarring.”

Ultra-marathon running and professional cycling have also been linked
with as much as a fivefold hike in atrial fibrillation, an irregular heart
rhythm, the researchers reported. There is also some suggestion that
long-term excessive exercise may be linked with coronary artery
calcification and large-artery wall stiffening, but more research is
warranted, they added.

To help paint a clearer picture of how exercise affects the heart,
O’Keefe explained, “You and I pump about five quarts of blood a minute
around our bodies. If we exercise hard, it might go up to 25 quarts per
minute. You’re demanding a lot of your heart. While the heart is an
extremely resilient organ and you can train it up and it can do amazing
things, we believe that over the long haul, it’s healthier for people to
do more moderate exercise.”

“Beyond 30 to 60 minutes a day, you reach a point of diminishing
returns,” he said.

If you crave high-intensity exercise, he said, try to stick to interval
training — smaller bursts at a time, instead of prolonged intensity.

Marathon runner and cardiologist Dr. James Eichelberger, an associate
professor of medicine in the cardiology division at the University of
Rochester School of Medicine and Dentistry, in New York, said while it is
true that athletes who train extremely can develop mild changes in heart
chamber volumes and even small leakage of cardiac biomarkers into the
bloodstream, “most of these changes normalize soon after cessation of
extreme exercise. Long-lasting negative effects are not clear, and most
likely do not negate the well-known long-term benefits.”

His advice: “Be consistent and avoid extremes if you are exercising
solely for health.” In other words, “Don’t be a weekend warrior.”

When it comes to suggesting weekly mileage guidelines, Eichelberger
hesitated. “I’m not sure there is really a correct distance that applies
to everybody. The idea that running less than 20 miles a week is good, and
running more than 20 is bad — I’d view that with a lot of skepticism. It
probably truly varies depending on a lot of different factors — patient
age, whether they’re in shape or not and other comorbidities, among other
factors,” he said.

He also noted that the heart’s not the only part of the body that’s
affected by extreme endurance training; it takes a toll on the
musculoskeletal system as well.

Lavie, an author on the second study as well as the first, said the
endurance athlete study shows that prolonged, intense exercise has its
risks.

“We know people are going to want to run marathons and triathlons, and
doing this occasionally is probably okay,” Lavie said. “But from a health
standpoint, it would be best not to become a very frequent long-endurance
exerciser.”

“Mix it up. Go do some yoga, or strength-training,” O’Keefe added.

More information

For more on running and longevity, go to Stanford University.

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