Psoriasis Patients May Face Higher Heart Risk

FRIDAY, March 16 (HealthDay News) — People with the painful skin
condition psoriasis may be at increased risk for health problems that
affect the heart, an expert says.

Excessive inflammation is a major feature of psoriasis. Chronic
inflammation is also a characteristic of insulin resistance, obesity,
abnormal cholesterol levels and cardiovascular disease, said Dr. Joel
Gelfand, an assistant professor of dermatology and epidemiology at the
University of Pennsylvania Perelman School of Medicine in
Philadelphia.

Gelfand noted that recent studies have linked these serious medical
conditions with psoriasis and it’s important for psoriasis patients
particularly those with severe psoriasis — to monitor themselves for
signs of these diseases.

The recent studies included research on more than 4,000 patients that
found that the more surface area of skin affected by psoriasis, the more
likely a patient is to have metabolic syndrome, which is a cluster of
conditions — obesity, high blood pressure, insulin resistance and
elevated triglyceride levels — associated with increased risk of heart
disease.

Another study found that patients with severe psoriasis die about five
years earlier than those who don’t have the disease, and about 50 percent
of the increased risk of death is due to cardiovascular disease, Gelfand
said in a news release from the American Academy of Dermatology. Other
studies have linked severe psoriasis to increased risk of major
cardiovascular events, such as heart attack.

Gelfand also explained in the news release that other research has
found that psoriasis patients have changes in cholesterol that can
increase the risk of hardening of the arteries, which can lead to heart
attack.

The report was slated for presentation Friday at the American Academy
of Dermatology’s annual meeting in San Diego. The data and conclusions of
research presented at medical meetings should be viewed as preliminary
until published in a peer-reviewed journal.

Although the report indicates an association between psoriasis and
cardiovascular risks, it did not prove a cause-and-effect
relationship.

“Future research is necessary to better determine how skin-disease
severity affects the risk of developing insulin resistance, obesity,
abnormal cholesterol levels and cardiovascular disease, and whether
successful treatment of psoriasis alters these risks,” Gelfand said in the
news release.

More information

The American Academy of Family Physicians has more about psoriasis.

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