Preteens More Likely to Report HPV Vaccine Side Effects

TUESDAY, April 3 (HealthDay News) — A new study finds that
preteen girls are more likely than older teens and adult women to
experience side effects after receiving the human papillomavirus (HPV)
vaccine, Gardasil.

However, the side effects are not serious and are similar to those
associated with other vaccines.

U.S. researchers surveyed about 900 girls and young women, aged 11 to
26, within two weeks after they received the Gardasil vaccine injection in
the upper arm. The vaccine protects against HPV infection, which is
sexually transmitted and a cause of cervical cancer.

Seventy-eight percent of the patients reported pain when receiving the
vaccine; 17 percent reported bruising or discoloration; 14 percent
reported swelling at the injection site; 15 percent reported dizziness,
and 1 percent of the girls fainted.

Younger patients were more likely to have received other vaccines —
such as tetanus, meningitis, and hepatitis A — at the same time they
received the HPV vaccine, and were also more likely to report side
effects, the study found.

For example, pain during the injection was reported by 84 percent of
girls aged 11 to 12 versus 74 percent of women aged 18 to 26. Dizziness
after receiving the vaccine was reported by 19 percent of girls aged 11 to
12 compared to 8 percent of women ages 18 to 26.

The U.S. Centers for Disease Control and Prevention-funded study was
published April 3 in the Journal of Women’s Health.

“Gardasil is an important cancer prevention vaccine, but too few girls
are getting it,” lead author Allison Naleway, a senior investigator with
the Kaiser Permanente Center for Health Research in Portland, Ore., said
in a Kaiser news release. “Our study found that young girls do have some
knowledge about the vaccine, but they need to know more. If these girls
and their parents know what to expect, they will likely be less afraid of
getting the vaccine.”

Dr. Mike Wilmington, a Kaiser Permanente pediatrician in Vancouver,
Wash., who was not involved in the study, said the side effects are
non-serious and very manageable.

“The main complaint I hear about is pain with the injection, but there
are ways to lessen the pain,” he said in the news release.”Some girls will
feel dizzy after this and other vaccines, so I follow CDC guidelines and
have them sit or lie down for a few minutes after receiving the
vaccine.”

The CDC recommends the three-dose Gardasil vaccination for girls aged
11 to 12, for older girls and women (aged 13 to 26) who did not receive
the vaccine when they were younger, for boys aged 11 to 12, and for older
boys and men (aged 13 to 21) who did not receive the vaccine when they
were younger.

Most of the girls and young women surveyed knew that the vaccine can
prevent cervical cancer and that three doses are suggested, but many were
unaware that Gardasil can also prevent genital warts and abnormal Pap
smears, the researchers said.

More information

The U.S. National Cancer Institute has more about HPV vaccines.

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