Not sleeping enough CAN damage your immune system and make you ill, says study

By
Mail Foreign Service

Last updated at 3:27 AM on 17th February 2012

A disturbed sleeping pattern can lead to illness, scientists say.

Researchers have found that the circadian clock – the genetic mechanism which regulates our sleep – controls the level of a gene vital to our immune system.

Scientists from Yale University linked the gene TLR-9 to the cycle in mice. When the gene was at its most active, it was able to respond best to bacteria and viruses and the mice responded better to infection and vaccinations.

Disrupted sleep: Everyone knows that a disrupted sleep pattern can lead to feelings of being run-down. But A Yale University study has linked a lack of sleep with a reduced immune system

Disrupted sleep: Everyone knows that a disrupted sleep pattern can lead to feelings of being run-down. But A Yale University study has linked a lack of sleep with a reduced immune system

In theory, the principles should also apply for the same gene in humans.

Disruptions to the cycle can make us more susceptible to illness, reports journal Immunity.

This suggests that jet lag may
contribute directly to illness and that there may be ideal times of the
day to receive vaccinations.

Professor Erol Fikrig said: ‘People
intuitively know that when their sleep patterns are disturbed, they are
more likely to get sick.’

Effects of jet lag: Long-haul flights and the disruption they have on sleeping patterns is one lifestyle choice identified in the report that can lower the immune system

Effects of jet lag: Long-haul flights and the disruption they have on sleeping patterns is one lifestyle choice identified in the report that can lower the immune system

He also suggested further study was
needed into how noise and artificial light in intensive care units could
be affecting patients.

He said: ‘Sleep patterns of patients
in intensive care are often disrupted because of the noise and prolonged
exposure to artificial light.

‘It will be important to investigate how these factors influence immune system response.’

Here’s what other readers have said. Why not add your thoughts,
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The comments below have not been moderated.

Margaret Thatcher said she survived (whilst being PM) on 4hrs a night sleep – did it do her any harm – no, did it do us any harm – yes.

I wonder how much this research cost? I could have told you that for nothing!

No hope then for us with newborns !

Ha ha ha really?! they had to do a study to figure that out did they?!

Well that’s obvious isn’t it?

It can make you tired as well.

Well I never go to bed before 1am as stay up late reading the DM every night and get about 6hrs sleep. Have not had any sort of cold or flu for 10 years – oh and have recently had to get up in at 4 am a few times to let cat in as I don’t have a cat flap! My mother wasnt into any kind of housework whatsoever and can remember lots of gardening and mud-pie making – Must have excellent immune system from that which will prepare me if I ever have to go into hospital.

There is no ideal time of the day to receive vaccinations. Vaccinations contain many toxic metals and toxic chemicals. You do not want to be poisoning your body with them. Don’t believe me – read the insert.

Changing our ridiculous time difference with Europe will give me another hour sleep before Mr Mistle Thrush wakes me up about 4.45 am through the summer.

There are a lot of pointless studies out there but this takes the biscuit. Please Yale, show me someone over the age of 5 that doesn’t already know this! I have been going to bed too late recently and now I have a sore throat. Unexpected? No. How will I cure it? Couple of early nights should do the trick! DM, the only reason I opened this article was to comment on how ridiculous it is! Please find interesting to write about.
– AC, Poole, 16/02/2012 17:40
While I agree we all know this, we didn’t know what caused this. Maybe scientific process should now stop in your eyes?

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