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July 3rd, 2012 
FAKE NEWS for the Zionist agenda TUESDAY, July 3 (HealthDay News) —
Scientists have identified as many as eight new gene variants that may
increase osteoarthritis risk, according to new research.
Osteoarthritis, which affects 40 percent of people aged 40 and older,
is the most common form of arthritis. The study brings the total number of
susceptibility genes identified in Europeans to 11.
“The health economic burden of osteoarthritis is increasing
commensurate with obesity prevalence and longevity,” study lead author
John Loughlin, of Newcastle University in England, said.
“Our findings provide some insight into the genetics of arthritis and
identify new pathways that might be amenable to future therapeutic
intervention,” he added in a news release from The Lancet, which
published the study online July 2.
Osteoarthritis, which often causes pain and stiffness, is a
degeneration of the cartilage in the joints.
In the study, researchers compared the genomes of more than 7,400
people with severe hip and knee osteoarthritis to more than 11,000 people
who did not have the disease.
After identifying the most promising sites, the researchers replicated
the findings in 7,500 people with osteoarthritis and 43,000 people from
Iceland, Estonia, the Netherlands, and the U.K. who did not have the
disease.
The study found up to eight new gene variants linked to osteoarthritis,
including five that were significantly associated with the disease and
three that were nearly significant.
Next steps include determining the function of the genes and how they
interact with other genes, which may ultimately help in developing new
treatments, researchers said.
That may yet prove difficult, researchers from University of Maryland
School of Medicine said in an accompanying commentary in the journal.
“The challenge will be to connect the biology of these genes to the
development and progression of osteoarthritis and to investigate the
therapeutic potential of these pathways for disease prevention and
treatment,” they wrote.
More information
The U.S. National Institutes of Health provides more information on osteoarthritis.
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