Heavy Coffee Intake May Affect Fertility Treatments: Study

TUESDAY, July 3 (HealthDay News) — Drinking five or more cups of
coffee a day may cut in half a woman’s chance of successful in vitro
fertilization treatment, a new study contends.

This level of caffeine consumption also reduces the live-birth rate
following in vitro fertilization (IVF) by 40 percent, the study authors
said.

The Danish researchers who conducted the study said the effects of a
five-cup-a-day coffee habit are similar to the negative effects of
smoking.

“Although we were not surprised that coffee consumption appears to
affect pregnancy rates in IVF, we were surprised at the magnitude of the
effect,” Dr. Ulrik Schioler Kesmodel, of the Fertility Clinic at Aarhus
University Hospital in Denmark, said in a news release from the European
Society of Human Reproduction and Embryology.

The new research found an apparent association between coffee
consumption and the success of fertility treatments, but it didn’t prove
that a cause-and-effect relationship exists.

Previous research investigating the link between caffeine and fertility
has yielded inconsistent results. The Danish researchers followed nearly
4,000 women undergoing IVF or intracytoplasmic sperm injection treatment
for infertility. Information on how much coffee the women drank was
collected at the beginning of treatment and at the start of each
additional round of treatment.

After taking into account other factors that could have an impact on
the women’s ability to get pregnant — such as age, smoking habits,
alcohol consumption, cause of infertility and body-mass index (a measure
of body fat based on height and weight) — the study showed the likelihood
of pregnancy was reduced by 50 percent in women who reported drinking five
or more cups of coffee daily at the start of treatment.

The researchers noted that no effect was found when the patients
reported coffee consumption of less than five cups.

“There is limited evidence about coffee in the literature, so we would
not wish to worry IVF patients unnecessarily,” Kesmodel said. “But it does
seem reasonable, based on our results and the evidence we have about
coffee consumption during pregnancy, that women should not drink more than
five cups of coffee a day when having IVF.”

The study’s findings were expected to be presented Tuesday at the
annual meeting of the European Society of Human Reproduction and
Embryology in Istanbul, Turkey.

Research presented at medical meetings should be viewed as preliminary
because it hasn’t undergone the same level of scrutiny required of studies
published in peer-reviewed journals.

More information

The U.S. National Institutes of Health has more information on in vitro fertilization.

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