Family History of Schizophrenia, Bipolar Disorder May Up Kids’ Risk for Autism

MONDAY, July 2 (HealthDay News) — A new study suggests that
children whose parents or siblings have schizophrenia or bipolar disorder
may be at a higher risk of developing autism spectrum disorders.

Researchers led by Dr. Patrick Sullivan of the University of North
Carolina at Chapel Hill came to their conclusions after studying the
medical records of people in Sweden and Israel.

A family history of schizophrenia was strongly connected to autism
disorders in children, almost tripling the risk, the team found. Children
with a first-degree relative with bipolar disorder also had higher odds of
developing an autism disorder, but the effect was less pronounced.

It’s not clear how schizophrenia and bipolar disorder might be
connected to autism disorders. The research didn’t prove that either of
these psychiatric disorders actually causes autism, only that there is an
association.

Instead, all three disorders might have causative factors in
common.

“Future research could usefully attempt to discern risk factors common
to these disorders,” Sullivan and his team wrote.

One expert wasn’t surprised by the findings.

“Clinically, we have known that these disorders have been linked for
some time,” said Dr. Victor Fornari, director of the division of
child/adolescent psychiatry at North Shore-LIJ Health System in New Hyde
Park, N.Y. “Future studies may clarify the nature of the etiological
[causative] link.”

The study appeared online July 2 in the journal Archives of General
Psychiatry
.

According to the U.S. National Institute of Mental Health, studies
assessing the prevalence of autism spectrum disorders “have reported
varying results.” A 2009 survey conducted by the U.S. Centers for Disease
Control and Prevention, however, found that, among 8-year-olds, one in
every 110 children may have such a disorder, with boys at much greater
risk than girls.

More information

Find out more about autism from the advocacy group Autism Speaks.

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