RSS Feed
March 7th, 2012 
FAKE NEWS for the Zionist agenda TUESDAY, March 6 (HealthDay News) — Some women who take
estrogen-only hormone replacement therapy to stave off hot flashes, night
sweats and other symptoms of menopause may be at lower risk for developing
breast cancer down the road, a news study says.
Hormone replacement therapy (HRT) fell from grace rather dramatically
after a large government-run trial, the U.S. Women’s Health Initiative,
was stopped early in 2002 because HRT was shown to increase the risk of
strokes and breast and ovarian cancer. Since that time, however, some
subtleties have emerged as researchers parsed the evidence further. For
example, short-term use of HRT is now deemed fairly safe for some women
who have severe menopausal symptoms.
The new study shows that longer-term use of estrogen-only therapy may
actually lower a woman’s odds of developing breast cancer. Estrogen-only
therapy is reserved for women who have had a hysterectomy; women with an
intact uterus who use HRT must take the hormone progestin with estrogen to
prevent uterine cancer.
“Women who have had a hysterectomy may be reassured that taking
estrogen by itself, short term, to relieve menopausal symptoms will not
increase their risk of breast cancer,” said study author Garnet Anderson
of the Women’s Health Initiative Clinical Coordinating Center at the Fred
Hutchinson Cancer Research Center in Seattle. Women should not take
estrogen to prevent breast cancer, she stressed.
The new findings were published in the March 7 online edition of The
Lancet Oncology.
The North American Menopause Society recently released a position
statement that backs up these findings. The group said starting
combination hormone therapy (both estrogen and progestin) around the time
of menopause to treat symptoms and stave off the brittle-bone disease
osteoporosis is safe for some women for three to five years. Estrogen
alone can be used for longer than the combination HRT, according to the
society.
The new study, which was partially funded by drug manufacturer Wyeth,
included more than 7,500 women from the Women’s Health Initiative who took
estrogen for about six years. Roughly five years after stopping treatment,
the women were 23 percent less likely to develop breast cancer when
compared to their counterparts who never used HRT.
Women in the estrogen group who did develop breast cancer were 63
percent less likely to die from the disease, compared to women who never
took it. The lower risk of breast cancer was seen only among women without
risk factors for breast cancer, such as a history of benign breast disease
or a strong family history of breast cancer, the study showed.
“The story is pretty clear about estrogen plus progestin — no matter
the age of the women, estrogen plus progestin increases [the risk of]
breast cancer, heart disease, stroke and blood clots,” Anderson said.
“These risks outweigh the benefits for all age groups.”
Why estrogen alone may lower breast cancer risk while adding progestin
seems to increase the risk is the million dollar question.
“There are hypotheses about the role of estrogen in breasts after a
woman has gone through menopause,” Anderson said. For example, “her breast
tissue, including any precancerous cells, may go through changes as a
result of menopause that make them susceptible to estrogen in a way that
discourages cell growth.”
Estrogen-only therapy is not without risks, however. For estrogen
alone, the Women’s Health Initiative data showed no overall effect of
estrogen on heart disease, but an increased risk of strokes and blood
clots.
Women are understandably confused about whether they should take
hormones to treat their menopausal symptoms, and for how long they can
safely use the therapy.
“The best use of estrogen-alone is in women with a hysterectomy who
need relief of hot flashes and night sweats and related menopausal
symptoms,” Anderson said. These benefits need to be weighed against a
woman’s risk of stroke or developing blood clots.
Dr. Lila Nachtigall, a professor of obstetrics and gynecology at NYU
Langone Medical Center in New York City, agreed that, when used on its
own, estrogen can still be safe and effective in treating the symptoms of
menopause in women who do not have a uterus.
“It looks very definite that the bad guy is progestin, not estrogen,”
Nachtigall said. Her advice is to use the lowest effective dose for the
shortest amount of time. If more women took estrogen, she said, there
would be a dent made in the epidemic of osteoporosis. “Millions of women
who never went on estrogen, even for a few years, are really losing bone,”
she said.
That said, estrogen does increase the risk of blood clots. “Women with
blood-clotting disorders should not take it,” Nachtigall said.
Commenting on the study, Dr. Stephanie Bernik, chief of surgical
oncology at Lenox Hill Hospital in New York City, said, “If you are
looking to reduce menopausal symptoms and don’t have an intact uterus,
[estrogen] is an option.” But estrogen-only therapy should not be
prescribed indiscriminately, she added.
“This applies only to women who have severe menopausal symptoms. We
are not saying that we should give women estrogen to reduce the risk of
breast cancer,” Bernik added.
More information
Learn more about the benefits and risks of
hormone replacement therapy through the North American Menopause
Society.
Views: 0
Posted in 
Tags: 
