Circulatory Disorder Not Studied Enough in Women, Experts Say

WEDNESDAY, Feb. 15 (HealthDay News) — Even though it increases
the risk of heart attack or stroke, peripheral artery disease is often
unrecognized and untreated in women, according to an American Heart
Association scientific statement released Wednesday.

Peripheral artery disease is a circulatory disorder caused by a buildup
of fat and other materials in the blood vessels outside the heart, usually
in the legs, feet and arms. If untreated, it can increase heart attack and
stroke risk, severely limit walking ability, and cause tissue death that
leads to limb amputation.

Because women with peripheral artery disease have a twofold to
threefold increased risk of stroke or heart attack, health care providers
should educate and test women at risk for peripheral artery disease, the
statement advised. It also called for more female-focused research into
the disease.

There are too few women enrolled in studies to provide a clear
understanding of how the disease progresses, or to accurately determine
the incidence and prevalence of peripheral artery disease in women,
according to the statement authors.

More studies of peripheral artery disease specifically in women are
needed, and results from previous studies should be pooled to obtain an
adequate sample size of women, they recommended.

The authors also called for research to help determine how gender may
affect the rate of development of peripheral artery disease, response to
medications, and potential benefits of vessel-opening procedures.

All heart-health promotion campaigns should provide specific education
about peripheral artery disease screening and treatment in women, the
authors added.

The statement is published Feb. 15 in the journal
Circulation.

Peripheral artery disease affects about 8 million people in the United
States, with nearly equal prevalence among women and men.

“The rate of deaths and the health care costs associated with
[peripheral artery disease] are at least comparable to those of heart
disease and stroke,” statement lead author Dr. Alan Hirsch, a professor of
medicine, epidemiology and community health at the Lillehei Heart
Institute at the University of Minnesota Medical School in Minneapolis,
said in a news release from the American Heart Association.

“Women, in particular, suffer an immense burden from peripheral artery
disease, yet current data demonstrate most women still remain unaware of
their risk,” Hirsch added.

More information

The U.S. National Heart, Lung, and Blood Institute has more about peripheral artery disease.

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