Cholesterol & Red Wine Could Aid in Fight Against Cancers Like Mesothelioma

June 15th, 2012

FAKE NEWS for the Zionist agenda

Eddie | 15 June 2012 | Health, News | American Heart Association, AntioxidantsAntioxidants, asbestos, asbestos fibers, AsbestosAsbestos, associate professor, associate professor in British Columbia, binding proteins, biochemistry department, Biochemistry Department at Simon Fraser University, british columbia canada, broad spectrum, Canada, cancer cell growth, cancer cells, cancer treatment, CancerCancer, Cancers, cause of heart disease, cell surfaces, Certain mesothelioma cell viability, cholesterol, CholesterolCholesterol, Christopher Beh, different cancer, dollar industry, genetic changes, Health_Medical_Pharma, heart attack, human malignant pleural mesothelioma, Korea, lung cancer, malignant cells, mesothelioma, MesotheliomaMesothelioma, natural components, necessary evil, negative connotation, novel treatments, outer membrane, OxysterolOxysterol, pharmaceutical products, ResveratrolResveratrol, s system, simon fraser university, slow cardiovascular disease, SterolsSterols, StilbenoidsStilbenoids, stop cancer, stroke, study researchers, the International Journal, tumor, tumors, university researcher, USD, Wine and healthWine and health | 0 Comments

Cholesterol normally carries a negative connotation, a necessary evil in cells and a major cause of heart disease, creating a billion dollar industry of specialization and pharmaceutical products to combat the problem.

According to the American Heart Association, too much cholesterol in a person’s system can build up on the walls of the arteries forming a plaque that can narrow the arteries leading to a heart attack or stroke. But in a recent study, researchers found that cholesterol has one redeeming quality. They found that cholesterol may be effective at fighting cancer, leading to novel treatments for all cancers, including those difficult to treat such as mesothelioma.

A Simon Fraser University researcher is among four scientists who argue that cholesterol may slow or stop cancer cell growth. Christopher Beh, an associate professor in the Biochemistry Department at Simon Fraser University in British Columbia, Canada, has specialized in studying cholesterol in his laboratory, hoping to better understand its impact on cell growth and human health.

Christopher Beh and his colleagues believe that cholesterol-binding proteins, or oxysterol binding proteins (ORPs), may slow or stop cancer cell growth. They discovered this while observing how cholesterol moves around inside cells in the fat’s journey to cell surfaces where it reinforces their outer membrane.

The researchers discovered that after genetic changes were made to the ORPs, they no longer binded to the cholesterol but continued to function and move around the cells. The altered ORPs also sparked other proteins that led to cell growth.

“First, cancer cells require ORPs to survive,” Beh said. “Second, other scientists have previously shown that a new class of natural components that look like steroids or cholesterol can kill a broad spectrum of different cancer cells.”

Beh said the next step for his team will be to determine exactly which proteins will respond to ORP activation and exactly what circumstances does cholesterol turn off ORP’s activation of them.

“Given that uncontrolled cell growth is a key feature in cancer, this means gaining a better understanding of the true purpose of cholesterol binding within cells, could be important in cancer treatment,” Beh said.

Mesothelioma is relevant to his research because it has been resistant to many traditional therapies that are unable to stop the growth of tumors. Mesothelioma, which is caused almost exclusively from an exposure to asbestos fibers, often is not diagnosed until it already has spread through the thin lining surrounding the lungs or heart.

It is diagnosed in an estimated 3,000 patients annually.

A daily glass of red wine, which for decades was recommended to help slow cardiovascular disease, might help stave off the progression of mesothelioma, according to a recent study from Korea.

Although red wine has been studied in previous cancer research, with mixed results, this was the first time it was done with mesothelioma specifically, based on a report last month in the International Journal of Molecular Medicine.

Researchers found that the organic compound Resveratrol, which is derived from the skin of red grapes and found in red wine, helped kill some malignant cells. Certain mesothelioma cell viability was decreased, and other cell death was increased when Resveratrol interacted with a specific protein known at Sp1.

“Our results strongly suggest that Sp1 is a novel molecular target of Res (Resvertrol) in human malignant pleural mesothelioma,” reported the study.

Although it’s too early to know how effective the red wine would be, researchers believed that it worked effectively to suppress tumor growth in laboratory mice that were used as part of the study.

Source: http://www.sfu.ca/pamr/media-releases/2012/study-finds-cancer-fighting-goodness-in-cholesterol.html