40Hz Audio and Visual Stimuli and Alzheimer’s

March 3rd, 2018

Awake Goy

40Hz Audio and Visual Stimuli and Alzheimer’s

March 2nd, 2018

In March 2015, Li-Huei Tsai set up a tiny disco for some of the mice in her laboratory. For an hour each day, she placed them in a box lit only by a flickering strobe. The mice â€” which had been engineered to produce plaques of the peptide amyloid-? in the brain, a hallmark of Alzheimerâ€™s disease â€” crawled about curiously. When Tsai later dissected them, those that had been to the mini dance parties had significantly lower levels of plaque than mice that had spent the same time in the dark1.

Tsai, a neuroscientist at Massachusetts Institute of Technology (MIT) in Cambridge, says she checked the result; then checked it again. â€œFor the longest time, I didnâ€™t believe it,â€� she says. Her team had managed to clear amyloid from part of the brain with a flickering light. The strobe was tuned to 40 hertz and was designed to manipulate the rodentsâ€™ brainwaves, triggering a host of biological effects that eliminated the plaque-forming proteins. Although promising findings in mouse models of Alzheimerâ€™s disease have been notoriously difficult to replicate in humans, the experiment offered some tantalizing possibilities. â€œThe result was so mind-boggling and so robust, it took a while for the idea to sink in, but we knew we needed to work out a way of trying out the same thing in humans,â€� Tsai says.

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